Over the centuries this building has worn many hats. It has been a court, a chapel, a pharmacy, a monastery-like retreat, a country oratory and a home. The relics of Saints Cosmas and Damian, the patron saints of Alberobello, were once housed here, and in the 1820s the Confraternity of the Most Holy Sacrament held its oratory within these walls. Its protection began early. The Trullo Sovrano was declared a national monument in 1923, five years before the Rione Monti district received the same recognition in 1928. On the seventh of December 1996, together with the Trulli of Alberobello, it entered the UNESCO World Heritage list. UNESCO singles it out as one of four specific locations in the property, a rare example of a two-storey building. In 2015 a ministerial decree also placed it on the list of sites of particular historical and artistic interest. Today the Trullo Sovrano is privately owned. It was restored in 1993 and is used for temporary exhibitions and cultural meetings. The Ministry of Culture notes that its interior is furnished in period taste, reconstructed from the memories of the oldest residents of Alberobello. In summer it has hosted theater, small orchestras, jazz and evenings of poetry.